Combination HIV Prevention Strategies Among Montreal Gay, Bisexual, and Other Men Who Have Sex with Men in the PrEP Era: A Latent Class Analysis.
Identifieur interne : 000034 ( Main/Exploration ); précédent : 000033; suivant : 000035Combination HIV Prevention Strategies Among Montreal Gay, Bisexual, and Other Men Who Have Sex with Men in the PrEP Era: A Latent Class Analysis.
Auteurs : Carla M. Doyle [Canada] ; Mathieu Maheu-Giroux [Canada] ; Gilles Lambert [Canada] ; Sharmistha Mishra [Canada] ; Herak Apelian [Canada] ; Marc Messier-Peet [Canada] ; Joanne Otis [Canada] ; Daniel Grace [Canada] ; Trevor A. Hart [Canada] ; David M. Moore [Canada] ; Nathan J. Lachowsky [Canada] ; Joseph Cox [Canada]Source :
- AIDS and behavior [ 1573-3254 ] ; 2021.
Descripteurs français
- KwdFr :
- Analyse de structure latente (MeSH), Bisexualité (MeSH), Comportement sexuel (MeSH), Homosexualité (MeSH), Homosexualité masculine (MeSH), Humains (MeSH), Infections à VIH (prévention et contrôle), Infections à VIH (épidémiologie), Mâle (MeSH), Prophylaxie pré-exposition (MeSH), Québec (épidémiologie).
- MESH :
- prévention et contrôle : Infections à VIH.
- épidémiologie : Infections à VIH, Québec.
- Analyse de structure latente, Bisexualité, Comportement sexuel, Homosexualité, Homosexualité masculine, Humains, Mâle, Prophylaxie pré-exposition.
English descriptors
- KwdEn :
- MESH :
- geographic , epidemiology : Quebec.
- epidemiology : HIV Infections.
- prevention & control : HIV Infections.
- Bisexuality, Homosexuality, Homosexuality, Male, Humans, Latent Class Analysis, Male, Pre-Exposure Prophylaxis, Sexual Behavior.
Abstract
Pre-exposure prophylaxis (PrEP) became publicly available in Quebec for gay, bisexual and other men who have sex with men (GBM) in 2013. We used baseline data from Engage, a cohort of GBM recruited by respondent-driven sampling, to examine patterns of combination HIV prevention use among Montreal GBM since PrEP became available. Latent class analysis, stratified by HIV status, was used to categorize GBM by self-reported use of biomedical and behavioural prevention strategies. Correlates of resulting classes were identified using multinomial logistic regression. Among HIV-negative/unknown GBM (n = 968), we identified four classes: low use of prevention (32%), condoms (40%), seroadaptive behaviour (21%), and biomedical (including PrEP; 7%). Those using prevention (condoms, seroadaptive behaviour, and biomedical) had a higher number of anal sex partners and were more likely to report a recent sexually transmitted infection diagnosis. GBM using biomedical prevention also had a higher level of formal education. Among GBM living with HIV (n = 200), we identified three classes: mainly antiretroviral treatment (ART) with viral suppression (53%), ART with viral suppression and condoms (19%), and ART with viral suppression and seroadaptive behaviour (18%). Again, the number of anal sex partners was higher among those using condoms and seroadaptive behaviours. Our findings show antiretroviral-based prevention, either alone or in combination with other strategies, is clearly a component of the HIV prevention landscape for GBM in Montreal. Nevertheless, PrEP uptake remains low, and there is a need to promote its availability more widely.
DOI: 10.1007/s10461-020-02965-4
PubMed: 32648063
PubMed Central: PMC7846508
Affiliations:
- Canada
- Colombie-Britannique , Ontario, Québec
- Montréal, Toronto, Vancouver
- Université McGill, Université de Toronto, Université de la Colombie-Britannique, Université du Québec à Montréal
Links toward previous steps (curation, corpus...)
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last="Messier-Peet">Marc Messier-Peet</name><affiliation wicri:level="1"><nlm:affiliation>Direction Régionale de Santé Publique de Montréal, Montreal, QC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Direction Régionale de Santé Publique de Montréal, Montreal, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation></author><author><name sortKey="Otis, Joanne" sort="Otis, Joanne" uniqKey="Otis J" first="Joanne" last="Otis">Joanne Otis</name><affiliation wicri:level="4"><nlm:affiliation>Département de Sexologie, Université du Québec à Montréal, Montreal, QC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Département de Sexologie, Université du Québec à Montréal, Montreal, QC</wicri:regionArea><orgName type="university">Université du Québec à Montréal</orgName><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Grace, Daniel" sort="Grace, Daniel" uniqKey="Grace D" first="Daniel" last="Grace">Daniel Grace</name><affiliation wicri:level="4"><nlm:affiliation>Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Dalla Lana School of Public Health, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Hart, Trevor A" sort="Hart, Trevor A" uniqKey="Hart T" first="Trevor A" last="Hart">Trevor A. Hart</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, Ryerson University, Toronto, ON, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Psychology, Ryerson University, Toronto, ON</wicri:regionArea><wicri:noRegion>ON</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:affiliation>Division of Social & Behavioural Sciences, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Social & Behavioural Sciences, Dalla Lana School of Public Health, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Moore, David M" sort="Moore, David M" uniqKey="Moore D" first="David M" last="Moore">David M. 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Lachowsky</name><affiliation wicri:level="1"><nlm:affiliation>School of Public Health and Social Policy, University of Victoria, Victoria, BC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>School of Public Health and Social Policy, University of Victoria, Victoria, BC</wicri:regionArea><wicri:noRegion>BC</wicri:noRegion></affiliation></author><author><name sortKey="Cox, Joseph" sort="Cox, Joseph" uniqKey="Cox J" first="Joseph" last="Cox">Joseph Cox</name><affiliation wicri:level="4"><nlm:affiliation>Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada. joseph.cox@mcgill.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC</wicri:regionArea><orgName type="university">Université McGill</orgName><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Direction Régionale de Santé Publique de Montréal, Montreal, QC, Canada. joseph.cox@mcgill.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Direction Régionale de Santé Publique de Montréal, Montreal, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Clinical Outcomes Research and Evaluation, Research Institute - McGill University Health Centre, Montreal, QC, Canada. joseph.cox@mcgill.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Clinical Outcomes Research and Evaluation, Research Institute - McGill University Health Centre, Montreal, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2021">2021</date><idno type="RBID">pubmed:32648063</idno><idno type="pmid">32648063</idno><idno type="doi">10.1007/s10461-020-02965-4</idno><idno type="pmc">PMC7846508</idno><idno type="wicri:Area/Main/Corpus">000128</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000128</idno><idno type="wicri:Area/Main/Curation">000128</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000128</idno><idno type="wicri:Area/Main/Exploration">000128</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Combination HIV Prevention Strategies Among Montreal Gay, Bisexual, and Other Men Who Have Sex with Men in the PrEP Era: A Latent Class Analysis.</title><author><name sortKey="Doyle, Carla M" sort="Doyle, Carla M" uniqKey="Doyle C" first="Carla M" last="Doyle">Carla M. Doyle</name><affiliation wicri:level="4"><nlm:affiliation>Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC</wicri:regionArea><orgName type="university">Université McGill</orgName><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Maheu Giroux, Mathieu" sort="Maheu Giroux, Mathieu" uniqKey="Maheu Giroux M" first="Mathieu" last="Maheu-Giroux">Mathieu Maheu-Giroux</name><affiliation wicri:level="4"><nlm:affiliation>Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC</wicri:regionArea><orgName type="university">Université McGill</orgName><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Lambert, Gilles" sort="Lambert, Gilles" uniqKey="Lambert G" first="Gilles" last="Lambert">Gilles Lambert</name><affiliation wicri:level="1"><nlm:affiliation>Direction Régionale de Santé Publique de Montréal, Montreal, QC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Direction Régionale de Santé Publique de Montréal, Montreal, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation></author><author><name sortKey="Mishra, Sharmistha" sort="Mishra, Sharmistha" uniqKey="Mishra S" first="Sharmistha" last="Mishra">Sharmistha Mishra</name><affiliation wicri:level="4"><nlm:affiliation>Department of Medicine, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Medicine, St. Michael's Hospital, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Institute of Medical Sciences, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>Institute of Health Policy Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Institute of Health Policy Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Apelian, Herak" sort="Apelian, Herak" uniqKey="Apelian H" first="Herak" last="Apelian">Herak Apelian</name><affiliation wicri:level="1"><nlm:affiliation>Direction Régionale de Santé Publique de Montréal, Montreal, QC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Direction Régionale de Santé Publique de Montréal, Montreal, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation></author><author><name sortKey="Messier Peet, Marc" sort="Messier Peet, Marc" uniqKey="Messier Peet M" first="Marc" last="Messier-Peet">Marc Messier-Peet</name><affiliation wicri:level="1"><nlm:affiliation>Direction Régionale de Santé Publique de Montréal, Montreal, QC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Direction Régionale de Santé Publique de Montréal, Montreal, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation></author><author><name sortKey="Otis, Joanne" sort="Otis, Joanne" uniqKey="Otis J" first="Joanne" last="Otis">Joanne Otis</name><affiliation wicri:level="4"><nlm:affiliation>Département de Sexologie, Université du Québec à Montréal, Montreal, QC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Département de Sexologie, Université du Québec à Montréal, Montreal, QC</wicri:regionArea><orgName type="university">Université du Québec à Montréal</orgName><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Grace, Daniel" sort="Grace, Daniel" uniqKey="Grace D" first="Daniel" last="Grace">Daniel Grace</name><affiliation wicri:level="4"><nlm:affiliation>Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Dalla Lana School of Public Health, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Hart, Trevor A" sort="Hart, Trevor A" uniqKey="Hart T" first="Trevor A" last="Hart">Trevor A. Hart</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, Ryerson University, Toronto, ON, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Psychology, Ryerson University, Toronto, ON</wicri:regionArea><wicri:noRegion>ON</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:affiliation>Division of Social & Behavioural Sciences, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Social & Behavioural Sciences, Dalla Lana School of Public Health, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Moore, David M" sort="Moore, David M" uniqKey="Moore D" first="David M" last="Moore">David M. Moore</name><affiliation wicri:level="1"><nlm:affiliation>BC Centre for Excellence in HIV/AIDS, Vancouver, BC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>BC Centre for Excellence in HIV/AIDS, Vancouver, BC</wicri:regionArea><wicri:noRegion>BC</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:affiliation>Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Faculty of Medicine, University of British Columbia, Vancouver, BC</wicri:regionArea><orgName type="university">Université de la Colombie-Britannique</orgName><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique </region></placeName></affiliation></author><author><name sortKey="Lachowsky, Nathan J" sort="Lachowsky, Nathan J" uniqKey="Lachowsky N" first="Nathan J" last="Lachowsky">Nathan J. Lachowsky</name><affiliation wicri:level="1"><nlm:affiliation>School of Public Health and Social Policy, University of Victoria, Victoria, BC, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>School of Public Health and Social Policy, University of Victoria, Victoria, BC</wicri:regionArea><wicri:noRegion>BC</wicri:noRegion></affiliation></author><author><name sortKey="Cox, Joseph" sort="Cox, Joseph" uniqKey="Cox J" first="Joseph" last="Cox">Joseph Cox</name><affiliation wicri:level="4"><nlm:affiliation>Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada. joseph.cox@mcgill.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC</wicri:regionArea><orgName type="university">Université McGill</orgName><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Direction Régionale de Santé Publique de Montréal, Montreal, QC, Canada. joseph.cox@mcgill.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Direction Régionale de Santé Publique de Montréal, Montreal, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Clinical Outcomes Research and Evaluation, Research Institute - McGill University Health Centre, Montreal, QC, Canada. joseph.cox@mcgill.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Clinical Outcomes Research and Evaluation, Research Institute - McGill University Health Centre, Montreal, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation></author></analytic><series><title level="j">AIDS and behavior</title><idno type="eISSN">1573-3254</idno><imprint><date when="2021" type="published">2021</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Bisexuality (MeSH)</term><term>HIV Infections (epidemiology)</term><term>HIV Infections (prevention & control)</term><term>Homosexuality (MeSH)</term><term>Homosexuality, Male (MeSH)</term><term>Humans (MeSH)</term><term>Latent Class Analysis (MeSH)</term><term>Male (MeSH)</term><term>Pre-Exposure Prophylaxis (MeSH)</term><term>Quebec (epidemiology)</term><term>Sexual Behavior (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Analyse de structure latente (MeSH)</term><term>Bisexualité (MeSH)</term><term>Comportement sexuel (MeSH)</term><term>Homosexualité (MeSH)</term><term>Homosexualité masculine (MeSH)</term><term>Humains (MeSH)</term><term>Infections à VIH (prévention et contrôle)</term><term>Infections à VIH (épidémiologie)</term><term>Mâle (MeSH)</term><term>Prophylaxie pré-exposition (MeSH)</term><term>Québec (épidémiologie)</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Quebec</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="prévention et contrôle" xml:lang="fr"><term>Infections à VIH</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à VIH</term><term>Québec</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Bisexuality</term><term>Homosexuality</term><term>Homosexuality, Male</term><term>Humans</term><term>Latent Class Analysis</term><term>Male</term><term>Pre-Exposure Prophylaxis</term><term>Sexual Behavior</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Analyse de structure latente</term><term>Bisexualité</term><term>Comportement sexuel</term><term>Homosexualité</term><term>Homosexualité masculine</term><term>Humains</term><term>Mâle</term><term>Prophylaxie pré-exposition</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Pre-exposure prophylaxis (PrEP) became publicly available in Quebec for gay, bisexual and other men who have sex with men (GBM) in 2013. We used baseline data from Engage, a cohort of GBM recruited by respondent-driven sampling, to examine patterns of combination HIV prevention use among Montreal GBM since PrEP became available. Latent class analysis, stratified by HIV status, was used to categorize GBM by self-reported use of biomedical and behavioural prevention strategies. Correlates of resulting classes were identified using multinomial logistic regression. Among HIV-negative/unknown GBM (n = 968), we identified four classes: low use of prevention (32%), condoms (40%), seroadaptive behaviour (21%), and biomedical (including PrEP; 7%). Those using prevention (condoms, seroadaptive behaviour, and biomedical) had a higher number of anal sex partners and were more likely to report a recent sexually transmitted infection diagnosis. GBM using biomedical prevention also had a higher level of formal education. Among GBM living with HIV (n = 200), we identified three classes: mainly antiretroviral treatment (ART) with viral suppression (53%), ART with viral suppression and condoms (19%), and ART with viral suppression and seroadaptive behaviour (18%). Again, the number of anal sex partners was higher among those using condoms and seroadaptive behaviours. Our findings show antiretroviral-based prevention, either alone or in combination with other strategies, is clearly a component of the HIV prevention landscape for GBM in Montreal. Nevertheless, PrEP uptake remains low, and there is a need to promote its availability more widely.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Curated" Owner="NLM"><PMID Version="1">32648063</PMID><DateCompleted><Year>2021</Year><Month>02</Month><Day>04</Day></DateCompleted><DateRevised><Year>2021</Year><Month>02</Month><Day>12</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1573-3254</ISSN><JournalIssue CitedMedium="Internet"><Volume>25</Volume><Issue>1</Issue><PubDate><Year>2021</Year><Month>Jan</Month></PubDate></JournalIssue><Title>AIDS and behavior</Title><ISOAbbreviation>AIDS Behav</ISOAbbreviation></Journal><ArticleTitle>Combination HIV Prevention Strategies Among Montreal Gay, Bisexual, and Other Men Who Have Sex with Men in the PrEP Era: A Latent Class Analysis.</ArticleTitle><Pagination><MedlinePgn>269-283</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s10461-020-02965-4</ELocationID><Abstract><AbstractText>Pre-exposure prophylaxis (PrEP) became publicly available in Quebec for gay, bisexual and other men who have sex with men (GBM) in 2013. We used baseline data from Engage, a cohort of GBM recruited by respondent-driven sampling, to examine patterns of combination HIV prevention use among Montreal GBM since PrEP became available. Latent class analysis, stratified by HIV status, was used to categorize GBM by self-reported use of biomedical and behavioural prevention strategies. Correlates of resulting classes were identified using multinomial logistic regression. Among HIV-negative/unknown GBM (n = 968), we identified four classes: low use of prevention (32%), condoms (40%), seroadaptive behaviour (21%), and biomedical (including PrEP; 7%). Those using prevention (condoms, seroadaptive behaviour, and biomedical) had a higher number of anal sex partners and were more likely to report a recent sexually transmitted infection diagnosis. GBM using biomedical prevention also had a higher level of formal education. Among GBM living with HIV (n = 200), we identified three classes: mainly antiretroviral treatment (ART) with viral suppression (53%), ART with viral suppression and condoms (19%), and ART with viral suppression and seroadaptive behaviour (18%). Again, the number of anal sex partners was higher among those using condoms and seroadaptive behaviours. Our findings show antiretroviral-based prevention, either alone or in combination with other strategies, is clearly a component of the HIV prevention landscape for GBM in Montreal. Nevertheless, PrEP uptake remains low, and there is a need to promote its availability more widely.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Doyle</LastName><ForeName>Carla M</ForeName><Initials>CM</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-5104-3068</Identifier><AffiliationInfo><Affiliation>Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Maheu-Giroux</LastName><ForeName>Mathieu</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lambert</LastName><ForeName>Gilles</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Direction Régionale de Santé Publique de Montréal, Montreal, QC, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mishra</LastName><ForeName>Sharmistha</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Medicine, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Institute of Health Policy Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Apelian</LastName><ForeName>Herak</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Direction Régionale de Santé Publique de Montréal, Montreal, QC, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Messier-Peet</LastName><ForeName>Marc</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Direction Régionale de Santé Publique de Montréal, Montreal, QC, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Otis</LastName><ForeName>Joanne</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Département de Sexologie, Université du Québec à Montréal, Montreal, QC, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Grace</LastName><ForeName>Daniel</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hart</LastName><ForeName>Trevor A</ForeName><Initials>TA</Initials><AffiliationInfo><Affiliation>Department of Psychology, Ryerson University, Toronto, ON, Canada.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Division of Social & Behavioural Sciences, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Moore</LastName><ForeName>David M</ForeName><Initials>DM</Initials><AffiliationInfo><Affiliation>BC Centre for Excellence in HIV/AIDS, Vancouver, BC, Canada.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lachowsky</LastName><ForeName>Nathan J</ForeName><Initials>NJ</Initials><AffiliationInfo><Affiliation>School of Public Health and Social Policy, University of Victoria, Victoria, BC, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cox</LastName><ForeName>Joseph</ForeName><Initials>J</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-7041-1556</Identifier><AffiliationInfo><Affiliation>Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada. joseph.cox@mcgill.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Direction Régionale de Santé Publique de Montréal, Montreal, QC, Canada. joseph.cox@mcgill.ca.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Clinical Outcomes Research and Evaluation, Research Institute - McGill University Health Centre, Montreal, QC, Canada. joseph.cox@mcgill.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>Engage Study Team</CollectiveName></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>#TE2-138299</GrantID><Acronym>CAPMC</Acronym><Agency> CIHR</Agency><Country>Canada</Country></Grant><Grant><GrantID>#CTN300</GrantID><Agency>Canadian HIV Trials Network, Canadian Institutes of Health Research</Agency><Country></Country></Grant><Grant><GrantID>#Engage</GrantID><Agency>Canadian Foundation for AIDS Research</Agency><Country></Country></Grant><Grant><GrantID>#1051</GrantID><Agency>Ontario HIV Treatment Network</Agency><Country></Country></Grant><Grant><GrantID>4500370314</GrantID><Agency>Public Health Agency of Canada</Agency><Country></Country></Grant><Grant><GrantID>#MSM2017LP-OD</GrantID><Agency>Canadian Blood Services</Agency><Country></Country></Grant><Grant><GrantID>#16863</GrantID><Agency>Michael Smith Foundation for Health Research</Agency><Country></Country></Grant><Grant><GrantID>#TE2-138299</GrantID><Acronym>CAPMC</Acronym><Agency> CIHR</Agency><Country>Canada</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>AIDS Behav</MedlineTA><NlmUniqueID>9712133</NlmUniqueID><ISSNLinking>1090-7165</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D001727" MajorTopicYN="N">Bisexuality</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015658" MajorTopicYN="Y">HIV Infections</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006716" MajorTopicYN="N">Homosexuality</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018451" MajorTopicYN="N">Homosexuality, Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000077272" MajorTopicYN="N">Latent Class Analysis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D065129" MajorTopicYN="Y">Pre-Exposure Prophylaxis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011792" MajorTopicYN="N" Type="Geographic">Quebec</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012725" MajorTopicYN="Y">Sexual Behavior</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Combination HIV prevention</Keyword><Keyword MajorTopicYN="N">HIV prevention strategies</Keyword><Keyword MajorTopicYN="N">Latent class analysis</Keyword><Keyword MajorTopicYN="N">Men who have sex with men</Keyword><Keyword MajorTopicYN="N">Pre-exposure prophylaxis</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>7</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2021</Year><Month>2</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate 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Lachowsky</name><name sortKey="Lambert, Gilles" sort="Lambert, Gilles" uniqKey="Lambert G" first="Gilles" last="Lambert">Gilles Lambert</name><name sortKey="Maheu Giroux, Mathieu" sort="Maheu Giroux, Mathieu" uniqKey="Maheu Giroux M" first="Mathieu" last="Maheu-Giroux">Mathieu Maheu-Giroux</name><name sortKey="Messier Peet, Marc" sort="Messier Peet, Marc" uniqKey="Messier Peet M" first="Marc" last="Messier-Peet">Marc Messier-Peet</name><name sortKey="Mishra, Sharmistha" sort="Mishra, Sharmistha" uniqKey="Mishra S" first="Sharmistha" last="Mishra">Sharmistha Mishra</name><name sortKey="Mishra, Sharmistha" sort="Mishra, Sharmistha" uniqKey="Mishra S" first="Sharmistha" last="Mishra">Sharmistha Mishra</name><name sortKey="Mishra, Sharmistha" sort="Mishra, Sharmistha" uniqKey="Mishra S" first="Sharmistha" last="Mishra">Sharmistha Mishra</name><name sortKey="Moore, David M" sort="Moore, David M" uniqKey="Moore D" first="David M" last="Moore">David M. Moore</name><name sortKey="Moore, David M" sort="Moore, David M" uniqKey="Moore D" first="David M" last="Moore">David M. Moore</name><name sortKey="Otis, Joanne" sort="Otis, Joanne" uniqKey="Otis J" first="Joanne" last="Otis">Joanne Otis</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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